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ARA 290

10mg

❄️Lyophilized powder

€43.99
1

Discount per Quantity

QuantityDiscountPrice per Unit
5 - 1010%€39.59
11 - 2015%€37.39
21+20%€35.19

Rigorous third-party testing

Every batch of our research chemicals and peptides undergoes independent third-party laboratory testing for purity and identity.

Total: €43.99

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For laboratory research use only by qualified professionals. Not for human or veterinary use. Not for ingestion, injection, topical application, diagnostic, therapeutic, prophylactic or cosmetic use.

ARA 290 is supplied as a catalogued research material in 10 mg. It is intended only for controlled analytical, biochemical and non-clinical laboratory workflows. The catalogue amount identifies the nominal vial presentation; it is not a dose or a use instruction.

ARA 290 is the development name for cibinetide, an 11-residue peptide beginning with pyroglutamate. The N-terminal cyclization and exact salt form must be confirmed for the batch before registry data are applied [1,2].

Product identity

Identity must be assigned to the exact batch rather than to a marketed name alone. Sequence, terminal modifications, conjugation, salt or counter-ion, hydration state and excipients may change the applicable mass and registry identifiers. The batch CoA and SDS take precedence over literature identifiers shown below.

Chemical properties and registry information

PropertyValue
Name and synonymsARA 290; cibinetide; pyroglutamyl EPO helix-B-derived peptide
Material categorySynthetic erythropoietin-derived 11-residue research peptide
Sequence or structural definitionpGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-OH; UEQLERALNSS, where U denotes pyroglutamate
Molecular formulaC51H84N16O21 for the free peptide; salts and solvates differ.
Average molecular mass1257.3 g/mol average mass for the free peptide.
CAS Registry Number1208243-50-8 for cibinetide free peptide, conditional on exact-form confirmation.
PubChem CIDCID 91810664 for cibinetide free peptide, conditional on exact-form confirmation.
Structural featuresN-terminal pyroglutamate and a free C-terminal carboxyl group; no glycosylation or full erythropoietin protein structure.
Physical formCatalogue vial; the exact physical state, salt or counter-ion and excipients are batch-specific and must be verified in the CoA and SDS.
Catalogue presentations10 mg
Batch identity and quality documentationLot-specific identity and available analytical reports must be verified against the CoA entry associated with the exact product size and batch.
Intended useAnalytical, biochemical and non-clinical laboratory research only; all human and veterinary uses are excluded.

Where an identifier is qualified or omitted, no unambiguous exact-form public assignment has been confirmed. Do not transfer an identifier from a related analogue, salt, conjugate or formulation.

Research context and evidence status

What the literature supports

Cibinetide has been studied as an erythropoietin-derived investigational peptide in receptor-signaling, tissue-response and early clinical research [2–4].

Evidence limitations

The available human studies were small and investigational and do not establish approved clinical efficacy. Findings for a study drug or full erythropoietin cannot authenticate or be transferred to this catalogue batch.

Cibinetide remains an investigational peptide; similarity to an erythropoietin-derived sequence does not make it erythropoietin or an authorized medicinal product.

ImportantResearch-use labeling does not itself determine the substance-specific legal status. The purchaser is responsible for confirming institutional authorization, local restrictions and lawful procurement, possession, import, export, storage and disposal.

Technical comparison

The comparison below is limited to structural and analytical distinctions. It does not compare clinical performance or recommend a use.

AspectThis catalogue materialComparator
IdentityARA 290/cibinetide 11-residue peptide, subject to batch confirmationFull-length glycosylated erythropoietin protein
Structural distinctionShort synthetic sequence with N-terminal pyroglutamate and no protein glycosylationLarge, folded and glycosylated protein with a distinct molecular identity
Analytical implicationConfirm pyroglutamate, sequence, termini, intact mass and counter-ionProtein-level identity and glycoform methods are not interchangeable with peptide analysis
What is not impliedNo conclusion about human or veterinary safety, efficacy, dosage, route, duration or interchangeability.No conclusion about human or veterinary safety, efficacy, dosage, route, duration or interchangeability.

Quality and batch documentation

Quality information is batch- and presentation-specific. Use only the report linked to the exact size and lot. A report listed for another size, lot or similarly named material must not be treated as evidence for this product.

Chromatographic area purity, identity, net peptide or analyte content, water or counter-ion content, sterility, endotoxin and elemental impurities are different measurements. One result does not establish the others. Only tests supported by a visible, matching report should be regarded as available.

Laboratory handling and storage

Store and handle only under the conditions stated on the product label, batch CoA and SDS. Keep the container secured, correctly identified and protected from contamination. Do not infer storage, solvent compatibility or stability from a related compound.

This page intentionally provides no reconstitution, administration or dosing instructions. Laboratory preparation, analytical method selection, risk assessment, personal protective equipment and waste disposal must be defined by the qualified institution and the applicable SDS.

Regulatory and legal status

This catalogue material is not offered as a medicine, medical device, in-vitro diagnostic, food, dietary supplement, cosmetic or veterinary product. It is not intended to diagnose, treat, cure, mitigate or prevent any disease or condition.

A research designation does not override medicinal-product, controlled-substance, chemical, customs or other substance-specific rules. Availability may be restricted by jurisdiction and by the purchaser's verified professional or institutional status.

Sources and references

References document identity and research context only. They do not constitute instructions for use or evidence that this catalogue batch is suitable for any human or veterinary purpose.

  1. [1] PubChem. Cibinetide, CID 91810664.
  2. [2] American Medical Association. Cibinetide USAN substance record.
  3. [3] Brines et al. Pilot randomized study of ARA 290. Molecular Medicine (2014).
  4. [4] Culver et al. Phase 2b investigational study of cibinetide. European Respiratory Journal (2017).

Frequently Asked Questions

What is this material intended for?

Controlled laboratory research by qualified professionals, including substantiated analytical, biochemical or non-clinical workflows. It is not intended for personal use.

Is the amount shown on the vial a dosage?

No. It is a nominal catalogue presentation used to identify the product variant. It is not a dose, concentration, administration schedule or preparation instruction.

Do the CAS number and PubChem CID apply to every batch form?

Only when the exact sequence or structure, termini, conjugation, salt or counter-ion and hydration state match. The batch CoA and SDS govern; a related-compound identifier must not be substituted.

What does an analytical purity result mean?

It is method- and report-specific. For example, an HPLC area percentage is not automatically the same as identity, net content, sterility, endotoxin status or absence of elemental impurities.

How should the material be stored and handled?

Follow the exact label, batch CoA and SDS, together with the institution's risk assessment. This page does not provide reconstitution or administration guidance.

May this material be used in humans or animals?

No. Human and veterinary use, including ingestion, injection, topical application, diagnosis, treatment, prevention and cosmetic use, is expressly excluded.

RESEARCH USE ONLY. NOT FOR HUMAN OR VETERINARY USE. THE PRODUCT NAME, VIAL AMOUNT AND LITERATURE REFERENCES MUST NOT BE INTERPRETED AS A DOSAGE, ADMINISTRATION INSTRUCTION OR MEDICAL CLAIM.

LABORATORY REAGENT – FOR RESEARCH PURPOSES ONLY

This product is not a drug or food and should be handled by qualified professionals in laboratory conditions. All product information is provided for educational purposes only.

Description

Information:

  • The product (substance) isn't a food or diet supplement and is not suitable for human consumption.
  • Keep out of children's reach
  • Keep container tightly closed.
  • Store in a dry, cool and shaded place; protect from moisture.
  • Store only in the original container.
  • Avoid contact during pregnancy and breast feeding.
  • Consult a doctor in the event of feeling unwell or having adverse effects related to the contact with the substance.